Gene information
Official symbol DAPK1
Official full name death associated protein kinase 1
Gene type protein-coding gene
Chromosome9q21.33
Alias symbolDAPK; ROCO3
Gene familyAnkyrin repeat domain containing; Death associated protein kinases; Roco domain containing
Resources
Entrez Gene 1612
HGNC HGNC:2674
Ensembl ENSG00000196730
Vega OTTHUMG00000020150
UCSC uc033czy.2
GO terms: 28 records
GO Description Category LogP Number of genes Detail
GO:0004672 protein kinase activity GO Molecular Functions -2.03527804 36 More
GO:0005525 GTP binding GO Molecular Functions -2.71464718 14 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006979 response to oxidative stress GO Biological Processes -17.6147653 58 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010506 regulation of autophagy GO Biological Processes -5.54010569 34 More
GO:0010508 positive regulation of autophagy GO Biological Processes -4.14985165 17 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0019001 guanyl nucleotide binding GO Molecular Functions -3.38049334 16 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0032412 regulation of ion transmembrane transporter activity GO Biological Processes -9.90560995 38 More
GO:0032561 guanyl ribonucleotide binding GO Molecular Functions -3.38049334 16 More
GO:0034341 response to interferon-gamma GO Biological Processes -10.8524889 26 More
GO:0034599 cellular response to oxidative stress GO Biological Processes -11.6255265 36 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0062197 cellular response to chemical stress GO Biological Processes -14.0979689 44 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
GO:2001257 regulation of cation channel activity GO Biological Processes -11.2578208 33 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04140 Autophagy - animal KEGG Pathway -3.52554737 16 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
gemcitabine PharmGKB 22293537 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
Chr9:87604996 hypomethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
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